Bardoxolone, CAS [[218600-44-3]]

Produktübersicht

• Artikelname: Bardoxolone, CAS [[218600-44-3]]
• Artikelnummer: MCE-HY-14909
• Hersteller Artikelnummer: HY-14909
• Alternativnummer: MCE-HY-14909-100MG,MCE-HY-14909-50MG,MCE-HY-14909-10MMX1ML,MCE-HY-14909-10MG,MCE-HY-14909-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: CDDO, RTA 401

Produktbeschreibung

Bardoxolone (CDDO, RTA 401) is a Nrf2 activator. Bardoxolone shows anti-SARS-CoV-2 3CLpro with IC50 of 27.99 µM. Bardoxolone activates the Nrf2 pathway and inhibits the NF-kappaB pathway. Bardoxolone can induce cells differentiation, apoptosis and shows antiproliferative activity against cancer cells. Bardoxolone can increase ROS and decrease intracellular GSH levels. Bardoxolone inhibits Z-VAD-FMK (HY-16658B)-induced necroptosis. Bardoxolone can be used for the research of cancer, inflammation and infection, such as SARS-CoV infection and glioblastoma[1][2][3].

Produkteigenschaften

• Molekulargewicht: 491.66
• Reinheit: 99.50
• CAS Nummer: [218600-44-3]
• Formel: C31H41NO4
• Target-Kategorie: Apoptosis,Glutathione Peroxidase,Keap1-Nrf2,Necroptosis,NF-kappaB,Reactive Oxygen Species (ROS),SARS-CoV

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound