Bardoxolone, CAS [[218600-44-3]]

Produktübersicht

• Artikelname: Bardoxolone, CAS [[218600-44-3]]
• Artikelnummer: MCE-HY-14909
• Hersteller Artikelnummer: HY-14909
• Alternativnummer: MCE-HY-14909-5MG,MCE-HY-14909-10MG,MCE-HY-14909-100MG,MCE-HY-14909-50MG,MCE-HY-14909-10MMX1ML
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: CDDO, RTA 401

Produktbeschreibung

Bardoxolone (RTA 401, CDDO) is an orally active activator of nuclear regulatory factor (NRf-2) and an inhibitor of SARS-CoV-2 3CL protease. Bardoxolone inhibits SARS-CoV-2 3CL protease with an EC50 value of 0.43 µM in vero cells. Bardoxolone also inhibits necroptosis in HT-29 cells with an EC50 value of 1.30 µM by blocking necrosome formation through inhibiting phosphorylation of RIPK1 and RIPK3. Bardoxolone can be used in research on COVID-19, TNF-induced systemic inflammatory response syndrome (SIRS), and cerebral ischemia-reperfusion injury[1][2].

Produkteigenschaften

• Molekulargewicht: 491.66
• Reinheit: 99.50
• CAS Nummer: [218600-44-3]
• Formel: C31H41NO4
• Target-Kategorie: Keap1-Nrf2,Necroptosis,SARS-CoV,Virus Protease

Anwendungsbeschreibung

• Anwendungsbeschreibung: Reference compound