ROS-generating agent 1 (Compound 2c) covalently modifies the Sec-498 residue of TrxR to generate ROS. ROS-generating agent 1 reduces intracellular TrxR protein level. ROS-generating agent 1 results in ROS-dependent apoptosis and ferroptosis of NCI-H460 cells. ROS-generating agent 1 has anti-cancer activities[1].
Molekulargewicht:
411.34
Reinheit:
99.11
CAS Nummer:
[2369030-41-9]
Formel:
C21H15F6NO
Target-Kategorie:
Apoptosis,Ferroptosis,Reactive Oxygen Species (ROS),TrxR
Anwendungsbeschreibung:
MCE Product type: Reference compound
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