ROS-generating agent 1 (Compound 2c) covalently modifies the Sec-498 residue of TrxR to generate ROS. ROS-generating agent 1 reduces intracellular TrxR protein level. ROS-generating agent 1 results in ROS-dependent apoptosis and ferroptosis of NCI-H460 cells. ROS-generating agent 1 has anti-cancer activities[1].
Molecular Weight:
411.34
Purity:
99.11
CAS Number:
[2369030-41-9]
Formula:
C21H15F6NO
Target:
Apoptosis,Ferroptosis,Reactive Oxygen Species (ROS),TrxR
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
