SB-1436 is an Cholinesterase (ChE) inhibitor, inhibits acetylcholinesterase (AChE), butyrylcholinesterase (BChE) and recombinant human acetylcholinesterase (rHuAChE) with IC50s of 0.176, 0.37 and 0.08 µM, respectively. SB-1436 inhibits AChE and BChE in a non-competitive manner with Kis of 0.046 and 0.115 µM, respectively. SB-1436 significantly stops the self-aggregation of Abeta, and can be used for neurological disease research[1].
Molekulargewicht:
405.89
CAS Nummer:
[2925298-08-2]
Formel:
C25H21ClFNO
Target-Kategorie:
Cholinesterase (ChE)
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
