SB-1436 is an Cholinesterase (ChE) inhibitor, inhibits acetylcholinesterase (AChE), butyrylcholinesterase (BChE) and recombinant human acetylcholinesterase (rHuAChE) with IC50s of 0.176, 0.37 and 0.08 µM, respectively. SB-1436 inhibits AChE and BChE in a non-competitive manner with Kis of 0.046 and 0.115 µM, respectively. SB-1436 significantly stops the self-aggregation of Abeta, and can be used for neurological disease research[1].
Molecular Weight:
405.89
CAS Number:
[2925298-08-2]
Formula:
C25H21ClFNO
Target:
Cholinesterase (ChE)
Application Notes:
MCE Product type: Reference compound
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