RIPK3-IN-3, CAS [[3052303-53-1]]

Produktübersicht

• Artikelname: RIPK3-IN-3, CAS [[3052303-53-1]]
• Artikelnummer: MCE-HY-149393
• Hersteller Artikelnummer: HY-149393
• Alternativnummer: MCE-HY-149393-10MMX1ML,MCE-HY-149393-5MG,MCE-HY-149393-10MG,MCE-HY-149393-100MG,MCE-HY-149393-50MG,MCE-HY-149393-25MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

RIPK3-IN-3 (compound 20) is a selective inhibitor of RIP kinase RIPK3 (IC50=10 nM). RIPK3 mediates the phosphorylation of Mixed Lineage Kinase (MLKL) and causes necroptosis, while RIPK3-IN-3 inhibits p-MLKL oligomerization and thereby inhibits necroptosis. RIPK3-IN-3 also downregulates CXCL5 secretion and inhibits AsPC-1 cell migration and invasion[1].

Produkteigenschaften

• Molekulargewicht: 305.36
• Reinheit: 95.98
• CAS Nummer: [3052303-53-1]
• Formel: C16H11N5S
• Target-Kategorie: Mixed Lineage Kinase,RIP kinase

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound