PROTAC AR-NTD degrader 1, CAS [[3032601-92-3]] Preis auf Anfrage
Artikelnummer:
MCE-HY-149434
Hersteller Artikelnummer:
HY-149434
Alternativnummer:
MCE-HY-149434-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
PROTAC AR-NTD antagonist 1 (compound 18) is a small molecule protein-targeting chimera (PROTACs) targeting the Androgen Receptor AR-V7. PROTAC AR-NTD antagonist 1 antagonizes the N-terminal domain of AR (AR-NTD), degrades AR-V7 protein, and induces apoptosis in prostate cancer (PC) cells. The efficiencies of PROTAC AR-NTD antagonist 1 in degrading AR-V7 in VCaP cells were 62.2% (1 µM) and 71.1% (5 µM), respectively[1].
Molekulargewicht:
771.30
CAS Nummer:
[3032601-92-3]
Formel:
C41H47ClN6O7
Target-Kategorie:
Androgen Receptor,Apoptosis,PROTACs
Anwendungsbeschreibung:
MCE Product type: Reference compound
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