PROTAC AR-NTD degrader 1, CAS [[3032601-92-3]] Preis auf Anfrage

Product Overview

• Article Name: PROTAC AR-NTD degrader 1, CAS [[3032601-92-3]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-149434
• Supplier Catalog Number: HY-149434
• Alternative Catalog Number: MCE-HY-149434-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

PROTAC AR-NTD antagonist 1 (compound 18) is a small molecule protein-targeting chimera (PROTACs) targeting the Androgen Receptor AR-V7. PROTAC AR-NTD antagonist 1 antagonizes the N-terminal domain of AR (AR-NTD), degrades AR-V7 protein, and induces apoptosis in prostate cancer (PC) cells. The efficiencies of PROTAC AR-NTD antagonist 1 in degrading AR-V7 in VCaP cells were 62.2% (1 µM) and 71.1% (5 µM), respectively[1].

Product Properties

• Molecular Weight: 771.30
• CAS Number: [3032601-92-3]
• Formula: C41H47ClN6O7
• Target: Androgen Receptor,Apoptosis,PROTACs

Application Notes

• Application Notes: Reference compound