hDHODH-IN-12 is a potent DHODH inhibitor with an IC50 value of 0.421 µM. DHODH is the rate-limiting enzyme in the de novo synthesis of pyrimidine which is essential in DNA/RNA Synthesis. hDHODH-IN-12 is present in the inner membrane of human mitochondria.hDHODH-IN-12 can be used for the research of lung cancer[1].
Molekulargewicht:
440.37
Formel:
C22H15F3N4O3
Target-Kategorie:
Dihydroorotate Dehydrogenase,DNA/RNA Synthesis
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
