hDHODH-IN-12 is a potent DHODH inhibitor with an IC50 value of 0.421 µM. DHODH is the rate-limiting enzyme in the de novo synthesis of pyrimidine which is essential in DNA/RNA Synthesis. hDHODH-IN-12 is present in the inner membrane of human mitochondria.hDHODH-IN-12 can be used for the research of lung cancer[1].
Molecular Weight:
440.37
Formula:
C22H15F3N4O3
Target:
Dihydroorotate Dehydrogenase,DNA/RNA Synthesis
Application Notes:
MCE Product type: Reference compound
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