Antiproliferative agent-23, CAS [[3049213-47-7]] Preis auf Anfrage

Produktübersicht

• Artikelname: Antiproliferative agent-23, CAS [[3049213-47-7]] Preis auf Anfrage
• Artikelnummer: MCE-HY-149918
• Hersteller Artikelnummer: HY-149918
• Alternativnummer: MCE-HY-149918-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

Antiproliferative agent-23 is a microtubule-destabilizing agent (MDA) and efficiently disturbes the tubulin-microtubule system. Antiproliferative agent-23 induces apoptosis via a mitochondrion-dependent pathway by downregulating the Bcl-2 protein, upregulating Bax and Cyt c proteins, and activating the caspase cascade. Antiproliferative agent-23 initiates reactive oxygen species (ROS)-mediated endoplasmic reticulum stress in A549/CDDP cells (cisplatin resistant cancer cell line) via the PERK/ATF4/CHOP signaling pathway. Antiproliferative agent-23 has anti-tumor activity[1].

Produkteigenschaften

• Molekulargewicht: 743.93
• CAS Nummer: [3049213-47-7]
• Formel: C23H28Cl3N3O6Pt
• Target-Kategorie: Apoptosis,Microtubule/Tubulin

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound