Antiproliferative agent-23, CAS [[3049213-47-7]] Preis auf Anfrage

Product Overview

• Article Name: Antiproliferative agent-23, CAS [[3049213-47-7]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-149918
• Supplier Catalog Number: HY-149918
• Alternative Catalog Number: MCE-HY-149918-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

Antiproliferative agent-23 is a microtubule-destabilizing agent (MDA) and efficiently disturbes the tubulin-microtubule system. Antiproliferative agent-23 induces apoptosis via a mitochondrion-dependent pathway by downregulating the Bcl-2 protein, upregulating Bax and Cyt c proteins, and activating the caspase cascade. Antiproliferative agent-23 initiates reactive oxygen species (ROS)-mediated endoplasmic reticulum stress in A549/CDDP cells (cisplatin resistant cancer cell line) via the PERK/ATF4/CHOP signaling pathway. Antiproliferative agent-23 has anti-tumor activity[1].

Product Properties

• Molecular Weight: 743.93
• CAS Number: [3049213-47-7]
• Formula: C23H28Cl3N3O6Pt
• Target: Apoptosis,Microtubule/Tubulin

Application Notes

• Application Notes: MCE Product type: Reference compound