KRas G12R inhibitor 1

Artikelnummer: MCE-HY-151523
Artikelname: KRas G12R inhibitor 1
Artikelnummer: MCE-HY-151523
Hersteller Artikelnummer: HY-151523
Alternativnummer: MCE-HY-151523-5MG,MCE-HY-151523-1MG
Hersteller: MedchemExpress
Kategorie: Biochemikalien
KRas G12R inhibitor 1 is a covalent inhibitor targeting the common oncogenic mutant KRas G12R with selectivity for the mutant arginine. KRas G12R inhibitor 1 possesses an alpha,beta-diketoamide and exploits strong nucleophilicity of the mutant cysteine and irreversibly binds in the Switch II region of KRas. KRas G12R inhibitor 1 can be researched for K-Ras (G12R)-driven cancer such as pancreatic ductal adenocarcinoma (PDAC)[1].
Molekulargewicht: 903.20
Reinheit: 98.19
Formel: C39H38ClF7N6O9
Target-Kategorie: Ras
Anwendungsbeschreibung: MCE Product type: Reference compound