Fmoc-L-Asn(EDA-N3)-OH, CAS [[2616562-74-2]] Preis auf Anfrage

Produktübersicht

• Artikelname: Fmoc-L-Asn(EDA-N3)-OH, CAS [[2616562-74-2]] Preis auf Anfrage
• Artikelnummer: MCE-HY-151829
• Hersteller Artikelnummer: HY-151829
• Alternativnummer: MCE-HY-151829-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

Fmoc-L-Asn(EDA-N3)-OH is a click chemistry reagent containing an azide group. This building block is reported in literature for the modification of Amanitin via Click Chemistry. Alpha-Amanitin is the deadliest member of the amatoxin peptide family produced by the death-cap mushroom A. phalloides. It is an orally available, rigid, bicyclic octapeptide and one of the most lethal known natural products (LD50 = 50-100 µg/kg) acting as highly selective allosteric inhibitor of the RNA polymerase II[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

Produkteigenschaften

• Molekulargewicht: 423.42
• CAS Nummer: [2616562-74-2]
• Formel: C21H21N5O5
• Target-Kategorie: ADC Linker

Anwendungsbeschreibung

• Anwendungsbeschreibung: Reference compound