Fmoc-L-Asn(EDA-N3)-OH, CAS [[2616562-74-2]] Preis auf Anfrage

Product Overview

• Article Name: Fmoc-L-Asn(EDA-N3)-OH, CAS [[2616562-74-2]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-151829
• Supplier Catalog Number: HY-151829
• Alternative Catalog Number: MCE-HY-151829-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

Fmoc-L-Asn(EDA-N3)-OH is a click chemistry reagent containing an azide group. This building block is reported in literature for the modification of Amanitin via Click Chemistry. Alpha-Amanitin is the deadliest member of the amatoxin peptide family produced by the death-cap mushroom A. phalloides. It is an orally available, rigid, bicyclic octapeptide and one of the most lethal known natural products (LD50 = 50-100 µg/kg) acting as highly selective allosteric inhibitor of the RNA polymerase II[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

Product Properties

• Molecular Weight: 423.42
• CAS Number: [2616562-74-2]
• Formula: C21H21N5O5
• Target: ADC Linker

Application Notes

• Application Notes: Reference compound