Nirogacestat (dihydrobromide), CAS [[1962925-29-6]]

Produktübersicht

• Artikelname: Nirogacestat (dihydrobromide), CAS [[1962925-29-6]]
• Artikelnummer: MCE-HY-15185B
• Hersteller Artikelnummer: HY-15185B
• Alternativnummer: MCE-HY-15185B-5MG,MCE-HY-15185B-100MG,MCE-HY-15185B-10MMX1ML,MCE-HY-15185B-50MG,MCE-HY-15185B-10MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: PF-3084014 (dihydrobromide), PF-03084014 (dihydrobromide)

Produktbeschreibung

Nirogacestat dihydrobromide (PF-3084014 dihydrobromide) is a reversible, orally bioavailable, noncompetitive, and selective gamma-secretase inhibitor with an IC50 of 6.2 nM. Inhibition of Notch signaling by Nirogacestat dihydrobromide while minimizing gastrointestinal toxicity presents a promising approach for research of Notch receptor-dependent cancers[1].

Produkteigenschaften

• Molekulargewicht: 651.47
• Reinheit: 99.9
• CAS Nummer: [1962925-29-6]
• Formel: C27H43Br2F2N5O
• Target-Kategorie: Apoptosis,gamma-secretase

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound