Nirogacestat (dihydrobromide), CAS [[1962925-29-6]]

Product Overview

• Article Name: Nirogacestat (dihydrobromide), CAS [[1962925-29-6]]
• Biozol Catalog Number: MCE-HY-15185B
• Supplier Catalog Number: HY-15185B
• Alternative Catalog Number: MCE-HY-15185B-5MG,MCE-HY-15185B-100MG,MCE-HY-15185B-10MMX1ML,MCE-HY-15185B-50MG,MCE-HY-15185B-10MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: PF-3084014 (dihydrobromide), PF-03084014 (dihydrobromide)

Product Description

Nirogacestat dihydrobromide (PF-3084014 dihydrobromide) is a reversible, orally bioavailable, noncompetitive, and selective gamma-secretase inhibitor with an IC50 of 6.2 nM. Inhibition of Notch signaling by Nirogacestat dihydrobromide while minimizing gastrointestinal toxicity presents a promising approach for research of Notch receptor-dependent cancers[1].

Product Properties

• Molecular Weight: 651.47
• Purity: 99.9
• CAS Number: [1962925-29-6]
• Formula: C27H43Br2F2N5O
• Target: Apoptosis,gamma-secretase

Application Notes

• Application Notes: MCE Product type: Reference compound