Ipatasertib (tosylate), CAS [[1491138-24-9]] Preis auf Anfrage

Produktübersicht

• Artikelname: Ipatasertib (tosylate), CAS [[1491138-24-9]] Preis auf Anfrage
• Artikelnummer: MCE-HY-15186C
• Hersteller Artikelnummer: HY-15186C
• Alternativnummer: MCE-HY-15186C-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: GDC-0068 (tosylate), RG7440 (tosylate)

Produktbeschreibung

Ipatasertib (GDC-0068) tosylate is an orally active, highly selective and ATP-competitive pan-Akt inhibitor with IC50 values of 5, 18, 8 nM for Akt1/2/3, respectively. Ipatasertib tosylate synchronously activates FoxO3a and NF-kappaB through inhibition of Akt leading to p53-independent activation of PUMA. Ipatasertib tosylate also induces apoptosis in cancer cells and inhibits tumor growth in xenograft mouse models[1][2].

Produkteigenschaften

• Molekulargewicht: 630.20
• CAS Nummer: [1491138-24-9]
• Formel: C31H40ClN5O5S
• Target-Kategorie: Akt,Apoptosis,Organoid

Anwendungsbeschreibung

• Anwendungsbeschreibung: Reference compound