Ipatasertib (tosylate), CAS [[1491138-24-9]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-15186C
Supplier Catalog Number:
HY-15186C
Alternative Catalog Number:
MCE-HY-15186C-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
GDC-0068 (tosylate), RG7440 (tosylate)
Ipatasertib (GDC-0068) tosylate is an orally active, highly selective and ATP-competitive pan-Akt inhibitor with IC50 values of 5, 18, 8 nM for Akt1/2/3, respectively. Ipatasertib tosylate synchronously activates FoxO3a and NF-kappaB through inhibition of Akt leading to p53-independent activation of PUMA. Ipatasertib tosylate also induces apoptosis in cancer cells and inhibits tumor growth in xenograft mouse models[1][2].
Molecular Weight:
630.20
CAS Number:
[1491138-24-9]
Formula:
C31H40ClN5O5S
Target:
Akt,Apoptosis,Organoid
Application Notes:
Reference compound
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