MC2590 is a potent pyridine-containing histone deacetylase (HDAC) inhibitor. MC2590 is an inhibitor of HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, and HDAC10 (class I/IIb-selective inhibitor) with IC50s of 0.015 µM-0.156 µM. MC2590 also inhibits HDAC isoforms HDAC4, HDAC5, HDAC7, HDAC9, HDAC11 with IC50s of 1.35 µM-3.98 µM. MC2625 induces G2/M cell cycle arrest and modulates pro- and anti-apoptotic microRNAs towards apoptosis induction[1].
Molekulargewicht:
347.37
Reinheit:
98.71
CAS Nummer:
[2284460-01-9]
Formel:
C20H17N3O3
Target-Kategorie:
Apoptosis,HDAC
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
