MC2590 is a potent pyridine-containing histone deacetylase (HDAC) inhibitor. MC2590 is an inhibitor of HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, and HDAC10 (class I/IIb-selective inhibitor) with IC50s of 0.015 µM-0.156 µM. MC2590 also inhibits HDAC isoforms HDAC4, HDAC5, HDAC7, HDAC9, HDAC11 with IC50s of 1.35 µM-3.98 µM. MC2625 induces G2/M cell cycle arrest and modulates pro- and anti-apoptotic microRNAs towards apoptosis induction[1].
Molecular Weight:
347.37
Purity:
98.71
CAS Number:
[2284460-01-9]
Formula:
C20H17N3O3
Target:
Apoptosis,HDAC
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
