Zomiradomide, CAS [[2655656-99-6]]

Produktübersicht

• Artikelname: Zomiradomide, CAS [[2655656-99-6]]
• Artikelnummer: MCE-HY-153368
• Hersteller Artikelnummer: HY-153368
• Alternativnummer: MCE-HY-153368-50MG,MCE-HY-153368-5MG,MCE-HY-153368-1MG,MCE-HY-153368-10MG,MCE-HY-153368-25MG,MCE-HY-153368-100MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: KT-413

Produktbeschreibung

Zomiradomide is an orally active PROTAC degrader for IRAK4 (DC50=6 nM), thereby inhibiting the NF-kappaB signaling pathway. Zomiradomide acts also as a molecular glue, recruiting Ikaros and Aiolos, and mediating their degradation (DC50 for Ikaros is 1 nM), thereby activating the type I IFN signaling pathway[1][2][3]. (Pink: target protein ligand PROTAC IRAK4 ligand-5 (HY-168311), Blue: E3 ligase ligand Thalidomide-4-Br (HY-W039116), Black: linker (HY-168313))

Produkteigenschaften

• Molekulargewicht: 871.97
• Reinheit: 95.43
• CAS Nummer: [2655656-99-6]
• Formel: C45H48F3N7O6S
• Target-Kategorie: IFNAR,IRAK,NF-kappaB,PROTACs

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound1