Olezarsen (sodium), CAS [[2298451-31-5]]

Produktübersicht

• Artikelname: Olezarsen (sodium), CAS [[2298451-31-5]]
• Artikelnummer: MCE-HY-153491A
• Hersteller Artikelnummer: HY-153491A
• Alternativnummer: MCE-HY-153491A-1MG,MCE-HY-153491A-5MG,MCE-HY-153491A-10MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: ISIS 678354 (sodium), IONIS-APOCIII-LRx (sodium), AKCEA-APOCIII-LRx (sodium)

Produktbeschreibung

Olezarsen (ISIS 678354,IONIS-APOCIII-LRx) sodium is a GalNAc-modified antisense oligonucleotide. Olezarsen sodium binds to APOC3 mRNA and induces its degradation via ribonuclease H1-mediated sense strand cleavage, thereby reducing hepatic apolipoprotein C-III (apoC-III) synthesis. Olezarsen sodium reduces plasma triglyceride, apolipoprotein B and non-high-density lipoprotein cholesterol levels. Olezarsen sodium is applicable to research related to familial chylomicronemia syndrome, hypertriglyceridemia and atherosclerotic cardiovascular disease[1][2][3].

Produkteigenschaften

• Molekulargewicht: 8684.86 (free acid)
• Reinheit: 96.53
• CAS Nummer: [2298451-31-5]
• Formel: C296H419N71Na20O154P20S19
• Target-Kategorie: Apolipoprotein

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Oligonucleotides