ALK-IN-24 is an orally active ALK inhibitor with an IC50 value of 1.7 nM. ALK-IN-24 also inhibits insulin receptor kinase with an IC50 value of 6 nM. ALK-IN-24 suppresses the proliferation of lung adenocarcinoma cells. ALK-IN-24 inhibits ALK-driven tumor growth in xenograft mouse models. ALK-IN-24 can be used in research related to non-small cell lung cancer[1].
Molekulargewicht:
556.08
CAS Nummer:
[2093414-37-8]
Formel:
C26H30ClN7O3S
Target-Kategorie:
Anaplastic lymphoma kinase (ALK),Insulin Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
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