ALK-IN-24 is an orally active ALK inhibitor with an IC50 value of 1.7 nM. ALK-IN-24 also inhibits insulin receptor kinase with an IC50 value of 6 nM. ALK-IN-24 suppresses the proliferation of lung adenocarcinoma cells. ALK-IN-24 inhibits ALK-driven tumor growth in xenograft mouse models. ALK-IN-24 can be used in research related to non-small cell lung cancer[1].
Molecular Weight:
556.08
CAS Number:
[2093414-37-8]
Formula:
C26H30ClN7O3S
Target:
Anaplastic lymphoma kinase (ALK),Insulin Receptor
Application Notes:
MCE Product type: Reference compound
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