EGFR-IN-77, CAS [[2222930-49-4]] Preis auf Anfrage

Produktübersicht

• Artikelname: EGFR-IN-77, CAS [[2222930-49-4]] Preis auf Anfrage
• Artikelnummer: MCE-HY-153605
• Hersteller Artikelnummer: HY-153605
• Alternativnummer: MCE-HY-153605-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

EGFR-IN-77 (Compound 4a) is a selective EGFRT790M/L858R inhibitor, with an IC50 of 0.101 µM against EGFRT790M/L858R, 0.477 µM against EGFRL858R, and 1.771 µM against wild-type EGFR. EGFR-IN-77 functionally inhibits the kinase activities of EGFRT790M/L858R, EGFRL858R and wild-type EGFR. EGFR-IN-77 exerts selective antiproliferative effects on EGFRT790M/L858R non-small cell lung cancer cells. EGFR-IN-77 can be used for the research of EGFRL858R/T790M double-mutant non-small cell lung cancer[1].

Produkteigenschaften

• Molekulargewicht: 472.54
• CAS Nummer: [2222930-49-4]
• Formel: C26H28N6O3
• Target-Kategorie: EGFR

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound1