EGFR-IN-77, CAS [[2222930-49-4]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-153605
Supplier Catalog Number:
HY-153605
Alternative Catalog Number:
MCE-HY-153605-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
EGFR-IN-77 (Compound 4a) is a selective EGFRT790M/L858R inhibitor, with an IC50 of 0.101 µM against EGFRT790M/L858R, 0.477 µM against EGFRL858R, and 1.771 µM against wild-type EGFR. EGFR-IN-77 functionally inhibits the kinase activities of EGFRT790M/L858R, EGFRL858R and wild-type EGFR. EGFR-IN-77 exerts selective antiproliferative effects on EGFRT790M/L858R non-small cell lung cancer cells. EGFR-IN-77 can be used for the research of EGFRL858R/T790M double-mutant non-small cell lung cancer[1].
Molecular Weight:
472.54
CAS Number:
[2222930-49-4]
Formula:
C26H28N6O3
Target:
EGFR
Application Notes:
MCE Product type: Reference compound1
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