NSC 194308, CAS [[90379-42-3]]

Artikelnummer: MCE-HY-153736
Artikelname: NSC 194308, CAS [[90379-42-3]]
Artikelnummer: MCE-HY-153736
Hersteller Artikelnummer: HY-153736
Alternativnummer: MCE-HY-153736-50MG,MCE-HY-153736-5MG,MCE-HY-153736-10MG,MCE-HY-153736-25MG
Hersteller: MedchemExpress
Kategorie: Biochemikalien
NSC 194308 is a U2AF2-RNA binding enhancer. NSC 194308 enhances association of the U2AF1S34F-U2AF2-SF1 ternary complex with DEK splice site RNA. NSC 194308 inhibits pre-mRNA splicing by stalling spliceosome assembly at the point where U2AF helps recruit U2 snRNP to the branchpoint. NSC 194308 enhances the binding of pre-mRNA to U2AF2, selectively triggering cell aptptosis and death in leukemia cell lines containing spliceosome mutations. NSC 194308 can be used for the research of leukemia[1][2].
Molekulargewicht: 306.44
Reinheit: 98.40
CAS Nummer: [90379-42-3]
Formel: C12H22N2O3S2
Target-Kategorie: Apoptosis,DNA/RNA Synthesis
Anwendungsbeschreibung: MCE Product type: Reference compound