BML-190, CAS [[2854-32-2]]

Artikelnummer: MCE-HY-15420
Artikelname: BML-190, CAS [[2854-32-2]]
Artikelnummer: MCE-HY-15420
Hersteller Artikelnummer: HY-15420
Alternativnummer: MCE-HY-15420-10MG,MCE-HY-15420-50MG,MCE-HY-15420-100MG,MCE-HY-15420-10MMX1ML,MCE-HY-15420-5MG,MCE-HY-15420-500MG
Hersteller: MedchemExpress
Kategorie: Biochemikalien
Alternative Synonym: Indomethacin morpholinylamide, IMMA
BML-190(IMMA) is a potent and selective CB2 receptor ligand (Ki values are 435 nM and > 2 µM for CB2 and CB1 respectively). IC50 Value: 435 nM(Ki CB2) Target:CB2 receptor in vitro: BML-190 increases the accumulation of cAMP, via forskolin-stimulated mechanism in HEK-293 cells. Alternate studies suggest that BML-190 reduces the toxicity of culture supernatants to SH-SY5Y human neutroblastoma cells. Various research suggests that BML-190 is an essential tool in studying the proliferation of neuroblastoma. BML-190 diminishes LPS-induced NO and IL-6 production in a concentration-dependent manner. BML-190 also inhibits LPS-induced PGE2 production and COX-2 induction. in vivo:
Molekulargewicht: 426.89
Reinheit: 99.53
CAS Nummer: [2854-32-2]
Formel: C23H23ClN2O4
Target-Kategorie: Cannabinoid Receptor
Anwendungsbeschreibung: MCE Product type: Reference compound