PF-543, CAS [[1415562-82-1]]

Artikelnummer: MCE-HY-15425
Artikelname: PF-543, CAS [[1415562-82-1]]
Artikelnummer: MCE-HY-15425
Hersteller Artikelnummer: HY-15425
Alternativnummer: MCE-HY-15425-100MG,MCE-HY-15425-10MG,MCE-HY-15425-5MG,MCE-HY-15425-50MG,MCE-HY-15425-25MG,MCE-HY-15425-10MMX1ML
Hersteller: MedchemExpress
Kategorie: Biochemikalien
Alternative Synonym: Sphingosine Kinase 1 Inhibitor II
PF-543 (Sphingosine Kinase 1 Inhibitor II) is a potent, selective, reversible and sphingosine-competitive SPHK1 inhibitor with an IC50 of 2 nM and a Ki of 3.6 nM. PF-543 is >100-fold selectivity for SPHK1 over SPHK2. PF-543 is an effective potent inhibitor of sphingosine 1-phosphate (S1P) formation in whole blood with an IC50 of 26.7 nM. PF-543 induces apoptosis, necrosis, and autophagy[1][2][3].
Molekulargewicht: 465.60
Reinheit: 99.85
CAS Nummer: [1415562-82-1]
Formel: C27H31NO4S
Target-Kategorie: Apoptosis,Autophagy,LPL Receptor,SphK
Anwendungsbeschreibung: Reference compound