22-(4'-py)-JA, CAS [[1178895-15-2]] Preis auf Anfrage

Produktübersicht

• Artikelname: 22-(4'-py)-JA, CAS [[1178895-15-2]] Preis auf Anfrage
• Artikelnummer: MCE-HY-155721
• Hersteller Artikelnummer: HY-155721
• Alternativnummer: MCE-HY-155721-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: 22-(4'-Pyridinecarbonyl) jorunnamycin A

Produktbeschreibung

22-(4'-py)-JA is a semisynthetic derivative of junamycin A (JA) that can be isolated from the Thai blue sponge (Xestospongia sp.). 22-(4'-py)-JA has antimetastatic activity and can inhibit AKT/mTOR/p70S6K signaling. 22-(4'-py)-JA inhibits tumor cell invasion and tube formation in human umbilical vein endothelial cells (HUVEC), downregulates metalloproteinases (MMP-2 and MMP-9), hypoxia-inducible factor 1alpha (HIF-1alpha) and vascular endothelial growth factor (VEGF). 22-(4'-py)-JA has potent anticancer activity against non-small cell lung cancer (NSCLC)[1].

Produkteigenschaften

• Molekulargewicht: 598.60
• CAS Nummer: [1178895-15-2]
• Formel: C32H30N4O8
• Target-Kategorie: Akt,mTOR

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Natural Products