Taltobulin (HTI-286), a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Taltobulin inhibits the polymerization of purified tubulin, disrupts microtubule organization in cells, and induces mitotic arrest, as well as apoptosis[1].
Molekulargewicht:
473.65
Reinheit:
99.90
CAS Nummer:
[228266-40-8]
Formel:
C27H43N3O4
Target-Kategorie:
ADC Payload,Apoptosis,Microtubule/Tubulin
Anwendungsbeschreibung:
MCE Product type: ADC Related
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