Taltobulin (HTI-286), a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Taltobulin inhibits the polymerization of purified tubulin, disrupts microtubule organization in cells, and induces mitotic arrest, as well as apoptosis[1].
Molecular Weight:
473.65
Purity:
99.90
CAS Number:
[228266-40-8]
Formula:
C27H43N3O4
Target:
ADC Payload,Apoptosis,Microtubule/Tubulin
Application Notes:
MCE Product type: ADC Related
* VAT and and shipping costs not included. Errors and price changes excepted