MeOIstPyrd is an anti-skin cancer agent. MeOIstPyrd inhibits cell proliferation, migration, and spheroid formation by activating the mitochondrial intrinsic apoptotic pathway. MeOIstPyrd induces DNA damage. MeOIstPyrd activates p53, and increases the half-life of p53 and stabilizes p53 by phosphorylating it at ser15. MeOIstPyrd binds to MDM2 in the p53 sub-pocket and blocks p53-MDM2 interaction[1].
Molekulargewicht:
304.37
Reinheit:
99.84
CAS Nummer:
[2308548-54-9]
Formel:
C14H16N4O2S
Target-Kategorie:
MDM-2/p53
Anwendungsbeschreibung:
MCE Product type: Reference compound
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