MeOIstPyrd is an anti-skin cancer agent. MeOIstPyrd inhibits cell proliferation, migration, and spheroid formation by activating the mitochondrial intrinsic apoptotic pathway. MeOIstPyrd induces DNA damage. MeOIstPyrd activates p53, and increases the half-life of p53 and stabilizes p53 by phosphorylating it at ser15. MeOIstPyrd binds to MDM2 in the p53 sub-pocket and blocks p53-MDM2 interaction[1].
Molecular Weight:
304.37
Purity:
99.84
CAS Number:
[2308548-54-9]
Formula:
C14H16N4O2S
Target:
MDM-2/p53
Application Notes:
MCE Product type: Reference compound
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