CaMKIIalpha-PHOTAC, CAS [[2481744-33-4]] Preis auf Anfrage

Artikelnummer: MCE-HY-156104
Artikelname: CaMKIIalpha-PHOTAC, CAS [[2481744-33-4]] Preis auf Anfrage
Artikelnummer: MCE-HY-156104
Hersteller Artikelnummer: HY-156104
Alternativnummer: MCE-HY-156104-1UNIT
Hersteller: MedchemExpress
Kategorie: Biochemikalien
CaMKIIalpha-PHOTAC is a photochemically targeted chimera (PHOTAC) targeting Ca2+/calmodulin-dependent protein kinase II alpha (CaMKIIalpha). Molecules such as PHOTAC can catalyze the ubiquitination and degradation of target proteins through the endogenous proteasome under specific wavelengths of light. CaMKIIalpha-PHOTAC reduces synaptic function under light conditions, and it attenuates the intensity of evoked field excitatory postsynaptic potentials in the mouse hippocampus in response to physiological stimuli. CaMKIIalpha-PHOTAC plays a critical role in maintaining long-term potentiation and memory capacity in subcellular dendritic domains[1].
Molekulargewicht: 1094.00
CAS Nummer: [2481744-33-4]
Formel: C54H58Cl2N10O11
Target-Kategorie: CaMK,PROTACs
Anwendungsbeschreibung: MCE Product type: Reference compound