CaMKIIalpha-PHOTAC, CAS [[2481744-33-4]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-156104
Supplier Catalog Number:
HY-156104
Alternative Catalog Number:
MCE-HY-156104-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
CaMKIIalpha-PHOTAC is a photochemically targeted chimera (PHOTAC) targeting Ca2+/calmodulin-dependent protein kinase II alpha (CaMKIIalpha). Molecules such as PHOTAC can catalyze the ubiquitination and degradation of target proteins through the endogenous proteasome under specific wavelengths of light. CaMKIIalpha-PHOTAC reduces synaptic function under light conditions, and it attenuates the intensity of evoked field excitatory postsynaptic potentials in the mouse hippocampus in response to physiological stimuli. CaMKIIalpha-PHOTAC plays a critical role in maintaining long-term potentiation and memory capacity in subcellular dendritic domains[1].
Molecular Weight:
1094.00
CAS Number:
[2481744-33-4]
Formula:
C54H58Cl2N10O11
Target:
CaMK,PROTACs
Application Notes:
MCE Product type: Reference compound
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