DHFR-IN-9, CAS [[3032441-13-4]] Preis auf Anfrage

Produktübersicht

• Artikelname: DHFR-IN-9, CAS [[3032441-13-4]] Preis auf Anfrage
• Artikelnummer: MCE-HY-156123
• Hersteller Artikelnummer: HY-156123
• Alternativnummer: MCE-HY-156123-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

DHFR-IN-9 (compound 8A) is a dihydrofolate reductase (DHFR) inhibitor that affects purine and thymidylate biosynthesis in cell proliferation and growth. DHFR-IN-9 inhibits methicillin-resistant Staphylococcus aureus (MRSA) ATCC 43300 (IC50=0.25 µg/mL) and has anti-infective effects in mouse models of systemic infection and thigh infection caused by it (dose: 2.5 mg /kg, 5 mg/kg, ip). DHFR-IN-9 has stronger anticancer activity than paclitaxel (Y-B0015) in a mouse model of breast cancer (dose: 2.5 mg/kg, ip, once every 3 days)[1].

Produkteigenschaften

• Molekulargewicht: 360.44
• CAS Nummer: [3032441-13-4]
• Formel: C19H16N6S
• Target-Kategorie: Bacterial,Dihydrofolate reductase (DHFR)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound