CDK9-Cyclin T1 PPI-IN-1, CAS [[2995336-58-6]] Preis auf Anfrage
Artikelnummer:
MCE-HY-156296
| Artikelname: |
CDK9-Cyclin T1 PPI-IN-1, CAS [[2995336-58-6]] Preis auf Anfrage |
| Artikelnummer: |
MCE-HY-156296 |
| Hersteller Artikelnummer: |
HY-156296 |
| Alternativnummer: |
MCE-HY-156296-1UNIT |
| Hersteller: |
MedchemExpress |
| Kategorie: |
Biochemikalien |
| CDK9-Cyclin T1 PPI-IN-1 (Compound B19) is a selective CDK9-Cyclin T1 protein-protein interaction (PPI) inhibitor. CDK9-Cyclin T1 PPI-IN-1 inhibits cell proliferation in TNBC MDA-MB-231 cells (IC50: 0.044 µM), and induces apoptosis. CDK9-Cyclin T1 PPI-IN-1 inhibits CDK9 transcription activity, reduces the phosphorylation of RNA Pol II CTD ser2. CDK9-Cyclin T1 PPI-IN-1 inhibits tumor growth in a TNBC 4T1 mouse model[1]. |
| Molekulargewicht: |
404.46 |
| CAS Nummer: |
[2995336-58-6] |
| Formel: |
C23H24N4O3 |
| Target-Kategorie: |
Apoptosis,CDK |
| Anwendungsbeschreibung: |
Reference compound |
