CDK9-Cyclin T1 PPI-IN-1, CAS [[2995336-58-6]] Preis auf Anfrage
Catalog Number:
MCE-HY-156296
| Article Name: |
CDK9-Cyclin T1 PPI-IN-1, CAS [[2995336-58-6]] Preis auf Anfrage |
| Biozol Catalog Number: |
MCE-HY-156296 |
| Supplier Catalog Number: |
HY-156296 |
| Alternative Catalog Number: |
MCE-HY-156296-1UNIT |
| Manufacturer: |
MedchemExpress |
| Category: |
Biochemikalien |
| CDK9-Cyclin T1 PPI-IN-1 (Compound B19) is a selective CDK9-Cyclin T1 protein-protein interaction (PPI) inhibitor. CDK9-Cyclin T1 PPI-IN-1 inhibits cell proliferation in TNBC MDA-MB-231 cells (IC50: 0.044 µM), and induces apoptosis. CDK9-Cyclin T1 PPI-IN-1 inhibits CDK9 transcription activity, reduces the phosphorylation of RNA Pol II CTD ser2. CDK9-Cyclin T1 PPI-IN-1 inhibits tumor growth in a TNBC 4T1 mouse model[1]. |
| Molecular Weight: |
404.46 |
| CAS Number: |
[2995336-58-6] |
| Formula: |
C23H24N4O3 |
| Target: |
Apoptosis,CDK |
| Application Notes: |
Reference compound |
