BRD9 c-1 (Compound 13-7) is a PROTAC BRD9 degrader[1]. BRD9 Degrader-1 has a micromolar binding affinity for BRD9 and a nanomolar affinity for the BRD9-VCB ternary complex. BRD9 Degrader-1 induces BRD9 proteasome degradation in HEK293T cells, which can be reversed by MLN4924 (HY-70062). (Blue: VH032-cyclopropane-F (HY-125905), Black: linker (HY-W763939), Pink: HY-168695)[1].
Molekulargewicht:
1017.25
Formel:
C49H65FN12O7S2
Target-Kategorie:
Epigenetic Reader Domain,PROTACs
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
