BRD9 c-1 (Compound 13-7) is a PROTAC BRD9 degrader[1]. BRD9 Degrader-1 has a micromolar binding affinity for BRD9 and a nanomolar affinity for the BRD9-VCB ternary complex. BRD9 Degrader-1 induces BRD9 proteasome degradation in HEK293T cells, which can be reversed by MLN4924 (HY-70062). (Blue: VH032-cyclopropane-F (HY-125905), Black: linker (HY-W763939), Pink: HY-168695)[1].
Molecular Weight:
1017.25
Formula:
C49H65FN12O7S2
Target:
Epigenetic Reader Domain,PROTACs
Application Notes:
MCE Product type: Reference compound
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