TT-012 is a specifical inhibitor of MITF (microphthalmia transcription factor) and destroys the MITFs dimer formation and DNA-binding ability. TT-012 inhibits the transcriptional activity of MITF in B16F10 melanoma cells. TT-012 inhibits the growth of high-MITF melanoma cells, and inhibits the tumor growth and metastasis with tolerable toxicity to liver and immune cells in animal models[1].
Molekulargewicht:
349.34
Reinheit:
99.76
CAS Nummer:
[1164471-33-3]
Formel:
C19H15N3O4
Target-Kategorie:
DNA/RNA Synthesis
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten