TT-012 is a specifical inhibitor of MITF (microphthalmia transcription factor) and destroys the MITFs dimer formation and DNA-binding ability. TT-012 inhibits the transcriptional activity of MITF in B16F10 melanoma cells. TT-012 inhibits the growth of high-MITF melanoma cells, and inhibits the tumor growth and metastasis with tolerable toxicity to liver and immune cells in animal models[1].
Molecular Weight:
349.34
Purity:
99.76
CAS Number:
[1164471-33-3]
Formula:
C19H15N3O4
Target:
DNA/RNA Synthesis
Application Notes:
MCE Product type: Reference compound
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