GSK-J4 (Standard), CAS [[1373423-53-0]] Preis auf Anfrage

Produktübersicht

• Artikelname: GSK-J4 (Standard), CAS [[1373423-53-0]] Preis auf Anfrage
• Artikelnummer: MCE-HY-15648BR
• Hersteller Artikelnummer: HY-15648BR
• Alternativnummer: MCE-HY-15648BR-5MG,MCE-HY-15648BR-10MG,MCE-HY-15648BR-25MG,MCE-HY-15648BR-50MG,MCE-HY-15648BR-100MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

GSK-J4 (Standard) is the analytical standard of GSK-J4. This product is intended for research and analytical applications. GSK-J4 is a potent dual inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A with IC50s of 8.6 and 6.6 µM, respectively. GSK-J4 inhibits LPS-induced TNF-alpha production in human primary macrophages with an IC50 of 9 µM. GSK J4 is a cell permeable proagent of GSK-J1[1][2][3]. GSK-J4 induces endoplasmic reticulum stress-related apoptosis[4].

Produkteigenschaften

• Molekulargewicht: 417.50
• CAS Nummer: [1373423-53-0]
• Formel: C24H27N5O2
• Target-Kategorie: Apoptosis,Histone Demethylase,Reference Standards

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference Standards