HJM-561, CAS [[2570251-68-0]]

Produktübersicht

• Artikelname: HJM-561, CAS [[2570251-68-0]]
• Artikelnummer: MCE-HY-156698
• Hersteller Artikelnummer: HY-156698
• Alternativnummer: MCE-HY-156698-25MG,MCE-HY-156698-5MG,MCE-HY-156698-100MG,MCE-HY-156698-50MG,MCE-HY-156698-10MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

HJM-561 is a selective and effective orally active EGFR PROTAC degrader. HJM-561 is able to overcome the triple EGFR mutations that are resistant to Osimertinib (HY-15772). HJM-561 exhibits potent degradation of EGFR Del19/T790M/C797S (DC50: 9.2 nM) and L858R/T790M/C797S (DC50: 5.8 nM), and has anti-tumor activity (pink: EGFR ligand (HY-12857), blue: CRBN ligand (HY-A0003), black: linker)[1].

Produkteigenschaften

• Molekulargewicht: 864.37
• Reinheit: 99.26
• CAS Nummer: [2570251-68-0]
• Formel: C45H51ClN9O5P
• Target-Kategorie: EGFR,PROTACs

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound