RIOK2-IN-1, CAS [[1088216-72-1]] Preis auf Anfrage
Artikelnummer:
MCE-HY-156792
Hersteller Artikelnummer:
HY-156792
Alternativnummer:
MCE-HY-156792-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
RIOK2-IN-1 (com 4) is a potent and selective RIOK2 inhibitor (Kd=150 nM), but has low cellular activity (IC50=14,600 nM). RIOK2 is an atypical kinase associated with a variety of human cancers and is involved in ribosome maturation and cell cycle progression. The small molecule inhibitor CQ211 (HY-147655), an improvement of RIOK2-IN-1 as the lead compound, has good in vivo and in vitro activity, inhibits the proliferation of MKN-1 and HT-29 cancer cells, and can xenograft MKN in mice -1 model inhibits tumor progression[1].
Molekulargewicht:
276.33
CAS Nummer:
[1088216-72-1]
Formel:
C18H16N2O
Target-Kategorie:
Ser/Thr Kinase
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
