RIOK2-IN-1, CAS [[1088216-72-1]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-156792
Supplier Catalog Number:
HY-156792
Alternative Catalog Number:
MCE-HY-156792-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
RIOK2-IN-1 (com 4) is a potent and selective RIOK2 inhibitor (Kd=150 nM), but has low cellular activity (IC50=14,600 nM). RIOK2 is an atypical kinase associated with a variety of human cancers and is involved in ribosome maturation and cell cycle progression. The small molecule inhibitor CQ211 (HY-147655), an improvement of RIOK2-IN-1 as the lead compound, has good in vivo and in vitro activity, inhibits the proliferation of MKN-1 and HT-29 cancer cells, and can xenograft MKN in mice -1 model inhibits tumor progression[1].
Molecular Weight:
276.33
CAS Number:
[1088216-72-1]
Formula:
C18H16N2O
Target:
Ser/Thr Kinase
Application Notes:
MCE Product type: Reference compound1
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