AP736 is a potent tyrosinase inhibitor (IC50 = 0.9 µM) with anti-melanogenesis activity in normal human melanocytes (IC50 = 0.11 µM). AP736 suppresses the expression of tyrosinase and TRP-1/2 by inhibiting the cAMP-PKA-CREB signalling axis, leading to reduced microphthalmia-associated transcription factor (MITF) transcripts and proteins. AP736 can be used for melanogenesis and hyperpigmentation research[1][2].
Molekulargewicht:
437.53
CAS Nummer:
[1365531-21-0]
Formel:
C26H31NO5
Target-Kategorie:
PKA,Tyrosinase
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
