RIPK1-IN-17, CAS [[3033385-59-7]]

Artikelnummer: MCE-HY-157039
Artikelname: RIPK1-IN-17, CAS [[3033385-59-7]]
Artikelnummer: MCE-HY-157039
Hersteller Artikelnummer: HY-157039
Alternativnummer: MCE-HY-157039-25MG,MCE-HY-157039-5MG,MCE-HY-157039-10MG
Hersteller: MedchemExpress
Kategorie: Biochemikalien
RIPK1-IN-17 is an orally active, selective RIPK1 inhibitor (Kd = 17 nM) and shows no significant inhibition to RIPK3. RIPK1-IN-17 specifically inhibits necroptosis rather than apoptosis by inhibiting RIPK1, RIPK3, and MLKL phosphorylation. RIPK1-IN-17 protects mice from hypothermia and death. RIPK1-IN-17 can be used for the study of necroptosis-related diseases such as inflammatory response syndrome (SIRS)[1].
Molekulargewicht: 529.51
Reinheit: 98.38
CAS Nummer: [3033385-59-7]
Formel: C26H19F4N3O3S
Target-Kategorie: Mixed Lineage Kinase,Necroptosis,RIP kinase
Anwendungsbeschreibung: MCE Product type: Reference compound